How Do PRP and PRF Work?
Every PRP or PRF treatment begins with a small blood draw. Your blood is then placed in a centrifuge, where it is carefully spun to separate and concentrate the platelet-rich components used for treatment.
These concentrated platelets contain growth factors that play a role in tissue repair, collagen support, and skin regeneration. In aesthetics, platelet-rich therapies are used to improve the appearance of skin aging, texture, hydration, and overall facial quality, though results vary by patient and treatment protocol.
The desired result is:
- Smoother, healthier-looking skin
- Improved skin texture and radiance
- Subtle softening of fine lines
- Gradual collagen support
- Refreshed under-eye or mid-face appearance
- Natural-looking rejuvenation using your own biology
PRP Lift vs PRF Lift: What’s the Difference?
PRP and PRF are closely related treatments, but they are not identical. Both are derived from your own blood, both contain platelets and growth factors, and both are used to support regenerative facial rejuvenation.
The main difference is how they are processed and how they behave once injected.
PRP is more fluid and releases growth factors more quickly, making it versatile for skin rejuvenation, injections, and combination treatments such as PRP microneedling.
PRF contains a fibrin matrix, which acts more like a natural scaffold. This allows for a slower, more sustained release of growth factors and makes PRF especially appealing for delicate areas where gradual tissue support is desired.
PRP Lift + PRP Microneedling
Can PRP Lift Be Combined with PRP Microneedling?
Yes. PRP Lift can be combined with PRP microneedling in the same appointment, depending on your skin goals and treatment plan.
When PRP is used for both microneedling and injectable treatment in one session, the prepared PRP is shared between the two techniques. This means a portion of the PRP is applied during microneedling to support skin texture and glow, while the remaining PRP is used for targeted injection into a smaller area.When PRP is used for both microneedling and injectable treatment in one session, the prepared PRP is shared between the two techniques. This means a portion of the PRP is applied during microneedling to support skin texture and glow, while the remaining PRP is used for targeted injection into a smaller area.When PRP is used for both microneedling and injectable treatment in one session, the prepared PRP is shared between the two techniques. This means a portion of the PRP is applied during microneedling to support skin texture and glow, while the remaining PRP is used for targeted injection into a smaller area.
For this reason, a combined PRP Microneedling + PRP Lift treatment is best understood as a hybrid regenerative facial treatment rather than a full PRP Lift.
It can be an excellent option for patients who want to:
Improve overall skin texture and radiance
Try a small targeted PRP injection area
Support collagen with a natural regenerative treatment
Begin with a lighter version of a full PRP Lift
Address one minimal area while still treating the full face with microneedling
For patients wanting more extensive injectable correction, a dedicated PRP Lift or PRF Lift appointment may be more appropriate.
PRP and PRF results develop gradually.
Most patients notice improvement over several weeks, with collagen-supporting changes continuing to refine over time.
PRP Lift
Brightening • Fluid • Versatile
PRP, or platelet-rich plasma, is a concentrated plasma treatment created from your own blood. It is typically more fluid than PRF, making it highly versatile for facial rejuvenation.
For a PRP Lift, PRP is injected into targeted areas of the face to support collagen, skin quality, and subtle regenerative improvement. PRP can also be combined with PRP microneedling, where a portion of the PRP is applied during microneedling to support overall skin texture, glow, and repair.
Why Patients Choose PRP Lift
Excellent for overall skin quality
Can be paired with PRP microneedling
Supports glow, texture, and collagen renewal
A good introduction to regenerative facial treatments
Ideal for patients wanting a lighter, more gradual approach
Best For
Crepey texture
Dullness
Fine lines
Early skin laxity
Overall facial refresh
Combination treatment with microneedling
PRF Lift
Slow-release • Regenerative • Restorative
PRF, or platelet-rich fibrin, is often considered a more advanced or “next generation” platelet concentrate. It is processed differently from PRP, typically with a slower spin and without anticoagulants, allowing a fibrin matrix to form. This matrix helps hold platelets and growth factors in place, creating a slower and more sustained regenerative effect.
For a PRF Lift, PRF is injected into carefully selected areas where subtle tissue support, collagen stimulation, and skin quality improvement are desired.
Why Patients Choose PRF Lift
Slower, more sustained growth-factor release
Beautiful for delicate facial areas
Supports gradual collagen and tissue refinement
Natural-looking rejuvenation
Often chosen for under-eye, mid-face, and crepey texture concerns
Best For
Under-eye rejuvenation
Early volume depletion
Fine lines and skin thinning
Crepey or delicate skin
Gradual regenerative support
Patients wanting a more natural alternative to filler-like correction
Interested in learning more? Book a free consultation for a personalized treatment plan with our expert Nurse Injectors
